Epidermal growth factor induces changes of interaction between epidermal growth factor receptor and actin in intact cells
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چکیده
منابع مشابه
Altered Expression of Epidermal Growth Factor Receptor (EGFR) in Glioma
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متن کاملEpidermal growth factor induces redistribution of actin and alpha-actinin in human epidermal carcinoma cells.
We have examined the possibility that epidermal growth factor (EGF)-induced morphological changes in human epidermoid carcinoma (A-431) cells are related to a reorganization of specific cytoskeletal elements affected by the hormone. It was found that EGF induced striking changes in the distribution of actin and a-actinin within these cells. After 30-45 min of exposure to EGF there was a marked ...
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A monoclonal antibody to the epidermal growth factor (EGF) receptor of A431 cells, denoted 2Dl-IgM, was generated after fusion of immunized BALB/c mouse spleen cells with SpZ/O-Ag14 myeloma cells, Specific binding of 2D1-IgM to the A431 cell-surface receptor for EGF was demonstrated by indirect immunofluorescence, immunoprecipitation, and immunoblot analysis. Scatchard analysis of lz6I-EGF bi...
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ژورنال
عنوان ژورنال: Acta Biochimica et Biophysica Sinica
سال: 2008
ISSN: 1672-9145,1745-7270
DOI: 10.1093/abbs/40.8.754